Publications

    PUBLICATION

    Extracellular vesicles bearing vimentin drive epithelial-mesenchymal transition 

    Sepideh Parvanian et al.

    Mol Cell Proteomics. 2025 Jul 4:101028. doi: 10.1016/j.mcpro.2025.101028. Online ahead of print.

    Published on July 6, 2025

    Epithelial-mesenchymal transition (EMT) is a key biological process in physiological and pathological conditions, spanning development, wound healing, and cancer. Vimentin, a key cytoskeletal intermediate filament Read more

    PUBLICATION

    Structural Repetition Detector for multi-scale quantitative mapping of molecular complexes through microscopy 

    Afonso Mendes et al.

    Nat Commun. 2025 Jul 1;16(1):5767. doi: 10.1038/s41467-025-60709-1.

    Published on July 2, 2025

    From molecules to organelles, cells exhibit recurring structural motifs across multiple scales. Understanding these structures provides insights into their functional roles. While super-resolution microscopy can Read more

    PUBLICATION

    Sketching T cell atlases in the single-cell era: challenges and recommendations 

    Itana Bojović et al.

    Immunol Cell Biol. 2025 Jun 29. doi: 10.1111/imcb.70040. Online ahead of print.

    Published on June 29, 2025

    Recent advances in single-cell technologies have enabled the creation of comprehensive cell atlases, reference maps of various cell types within organisms. Here we specifically focus Read more

    PUBLICATION

    In situ construction of ossification micro-units for critical bone regeneration via sustained lifting of epigenetic suppression 

    Wu Yang et al.

    J Control Release. 2025 Jun 23:113978. doi: 10.1016/j.jconrel.2025.113978. Online ahead of print.

    Published on June 25, 2025

    Critical-sized bone defects present significant clinical challenges due to insufficient stem cell recruitment, epigenetic suppression of osteogenesis, and inadequate mineralization. Among the epigenetic suppression mechanisms, Read more

    PUBLICATION

    Cytoskeletal crosstalk in macrophages: Vimentin drives ECM remodeling in tumor invasion and tissue plasticity 

    John E Eriksson et al.

    Dev Cell. 2025 Jun 23;60(12):1655-1657. doi: 10.1016/j.devcel.2025.05.015.

    Published on June 24, 2025

    In this issue of Developmental Cell, Huang et al. assess the role of vimentin intermediate filaments during extracellular matrix (ECM) degradation by macrophages. Vimentin stabilizes Read more

    PUBLICATION

    Integrin β1 activity controls colony morphology during human pluripotent stem cell state transitions 

    Maria E Taskinen et al.

    Stem Cell Reports. 2025 Jun 17:102538. doi: 10.1016/j.stemcr.2025.102538. Online ahead of print.

    Published on June 20, 2025

    Integrin β1-mediated adhesion is dispensable in early mouse embryogenesis (pre-implantation) but indispensable post-implantation, suggesting distinct roles for β1-integrin-mediated adhesions in the naive (pre-implantation) versus primed Read more

    PUBLICATION

    The Next Frontier: Unveiling Novel Approaches for Combating Multidrug-Resistant Bacteria 

    Praveen Mallari et al.

    Pharm Res. 2025 Jun 16. doi: 10.1007/s11095-025-03871-x. Online ahead of print.

    Published on June 16, 2025

    CONCLUSION: Despite the substantial obstacles to getting bench findings to the patient, numerous scientists are still working towards this goal. Both the application of antibiotic Read more

    PUBLICATION

    A metabolite-based resistance mechanism against malaria 

    Ana Figueiredo et al.

    Science. 2025 Jun 12;388(6752):eadq6741. doi: 10.1126/science.adq6741. Epub 2025 Jun 12.

    Published on June 12, 2025

    Jaundice is a common presentation of Plasmodium falciparum malaria, which arises from the accumulation of circulating bilirubin. It is not understood whether it represents an Read more

    PUBLICATION

    NRF2-mediated persistent adaptation of oesophageal adenocarcinoma cells to HER2 inhibition 

    Wei Zhang et al.

    Oncogene. 2025 Jun 5. doi: 10.1038/s41388-025-03459-0. Online ahead of print.

    Published on June 5, 2025

    The human epidermal growth factor receptor 2 (HER2, also known as ERBB2) is a commonly over-expressed oncoprotein in oesophageal adenocarcinoma (OAC). Nonetheless, HER2-blocking agents have Read more

    PUBLICATION

    Biochemical and structural characterization of chlorite dismutase enzyme from Pseudomonas aeruginosa 

    Dimitrios V Nokas et al.

    FEBS J. 2025 Jun 3. doi: 10.1111/febs.70151. Online ahead of print.

    Published on June 3, 2025

    Industrialization and urbanization have caused serious contamination of water bodies, and the removal of chemical contaminants has become a major challenge. Chlorite is a harmful Read more

    PUBLICATION

    A guide to heat shock factors as multifunctional transcriptional regulators 

    Hendrik S E Hästbacka et al.

    FEBS J. 2025 Jun 2. doi: 10.1111/febs.70139. Online ahead of print.

    Published on June 2, 2025

    The heat shock factors (HSFs) form a family of transcription factors, which are evolutionarily conserved in eukaryotes. They are best known as transcriptional regulators of Read more

    PUBLICATION

    Proliferation of Human Cervical Cancer Cells Responds to Surface Properties of Bicomponent Polymer Coatings 

    Emil Rosqvist et al.

    Nanomaterials (Basel). 2025 May 9;15(10):716. doi: 10.3390/nano15100716.

    Published on May 27, 2025

    The proliferation of human cervical cancer (Hela) cells was investigated on a series of nanostructured polymer latex surfaces. The physico-chemical properties of the surfaces, composed Read more